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Medical abortion became an alternative method of abortion with the availability of prostaglandin analogs in the 1970s and the antiprogestogen mifepristone (also known as RU-486) in the 1980s.The most common early first-trimester medical abortion regimens use mifepristone in combination with a prostaglandin analog (misoprostol or gemeprost) up to 9 weeks gestational age, methotrexate in combination with a prostaglandin analog up to 7 weeks gestation, or a prostaglandin analog alone.

Dilation and evacuation (D&E) consists of opening the cervix of the uterus and emptying it using surgical instruments and suction.Medical abortion using the prostaglandin analog misoprostol alone is less effective and more painful than medical abortion using a combined regimen of mifepristone and misoprostol or surgical abortion.For example, the question of a link between induced abortion and breast cancer has been investigated extensively.The health risks of abortion depend principally upon whether the procedure is performed safely or unsafely.The World Health Organization defines unsafe abortions as those performed by unskilled individuals, with hazardous equipment, or in unsanitary facilities.

Dilation and evacuation (D&E) consists of opening the cervix of the uterus and emptying it using surgical instruments and suction.

Medical abortion using the prostaglandin analog misoprostol alone is less effective and more painful than medical abortion using a combined regimen of mifepristone and misoprostol or surgical abortion.

For example, the question of a link between induced abortion and breast cancer has been investigated extensively.

The health risks of abortion depend principally upon whether the procedure is performed safely or unsafely.

The World Health Organization defines unsafe abortions as those performed by unskilled individuals, with hazardous equipment, or in unsanitary facilities.

For this reason, labor induced abortion is legally risky in the U. Reported methods of unsafe, self-induced abortion include misuse of misoprostol, and insertion of non-surgical implements such as knitting needles and clothes hangers into the uterus.